- Results from a clinical trial showed that people with mild cognitive impairment who were given a probiotic for 30 days scored higher on cognitive tests.
- After the trial, the gut microbiome of participants who took probiotics contained less of a type of bacteria associated with cognitive impairment.
- The findings suggest that manipulating gut bacteria could hold promise for addressing cognitive impairment and other chronic conditions.
A clinical trial suggests that treatment with a probiotic could help people with mild cognitive impairment (MCI) regain cognitive function.
With the
During the double-blind randomized trial, people with cognitive impairment received a daily probiotic — Lactobacillus rhamnosus GG — for three months, after which their scores on cognitive tests improved.
Analyzing participants’ stool samples, the researchers found substantial levels of Lactobacillus rhamnosus GG, or LGG, as well as a reduction in the amount of another family of bacteria, Prevotella, often observed in people with cognitive decline.
These changes suggest a beneficial shift in the composition of participants’
“LGG [bacteria] emerged as a potential therapeutic probiotic based on numerous previous animal studies, which demonstrated its positive effects on several physiological conditions. LGG is also known for its acid tolerance and its ability to adhere in the gut, which makes it an effective probiotic.”
– Mashael R. Aljumaah, lead study author
The research is being presented at the NUTRITION 2023 gathering in Boston, MA, this week. The clinical trial results were…
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