Researchers labeled the protein a “gerozyme” because of its link with aging
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As people age, their muscles tend to dwindle and weaken, especially with lack of use. With continued muscle loss, daily tasks are harder to perform and the risk of falling increases. One research team is teasing apart what’s behind this muscle loss by focusing on an enzyme associated with aging, which they’ve named a “gerozyme.”
The enzyme is 15-hydroxyprostaglandin dehydrogenase, or 15-PGDH. It breaks down a protein called prostaglandin E2. That protein activates the proliferation of muscle stem cells, regenerating damaged muscles.
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