- Heart failure affects more than 26 million people globally.
- Heart failure is prevalent in people with aortic stenosis.
- Researchers from Centro Nacional de Investigaciones Cardiovasculares found stimulation of the beta-3 adrenergic receptor in heart cells helps protect and prevent heart failure from aortic stenosis in a mouse model.
Heart failure is
Surgery, such as heart valve repair or
Now, researchers from Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a potential new therapeutic target for the prevention of heart failure linked to aortic stenosis using
Their study was recently published in the journal Basic Research in Cardiology.
Stenosis in the heart occurs when the heart valves become narrowed or blocked and do not open properly.
There are four main types of heart valve stenosis:
Aortic stenosis is the most common type of valve stenosis and refers to a problem with theaortic valve , halting blood circulating from the left ventricle to theaorta .Tricuspid stenosis impacts how blood moves between the upper and lower portions of the heart’s right side.Mitral stenosis affects how blood flows between the upper and lower portions of the left side of the heart.Pulmonary stenosis restricts blood flow from the lower right chamber to the pulmonary arteries and lungs.
Stenosis of the heart does not always generate noticeable symptoms.
If it does, symptoms may include:
Aortic stenosis mainly affects people
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