- Researchers investigated the effects of a genetic predisposition to high caffeine levels on measures of body fat, type 2 diabetes risk, and cardiovascular risk.
- They found that a higher genetic predisposition to higher caffeine levels is linked to reduced body fat and type 2 diabetes risk.
- Further studies are needed to confirm the results.
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How much these benefits come from caffeine, however, is unknown. One
Understanding more about how caffeine intake influences the development of cardiometabolic conditions could aid the development of dietary strategies to reduce their risk.
Recently, researchers investigated the effect of genetic predisposition to higher caffeine levels in the blood.
They found that a genetic predisposition to higher caffeine levels in the blood is linked to a lower risk for type 2 diabetes.
The study was published in BMJ Medicine.
For the study, the researchers examined data that came from a genome-wide association meta-analysis of 9,876 individuals of mostly European ancestry.
They used the data to examine two common genetic variants — CYP1A2 and AHR genes — in their analysis. These genes slow down caffeine metabolism, meaning that for those carrying the variants, less coffee needs to be drunk in order to have elevated levels of caffeine in their blood, compared to those who metabolize it quickly.
Researchers also collected data on body fat, type 2 diabetes risk, and risk for…
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