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Antibiotic neomycin may protect against the flu, COVID-19

Medical News Today by Medical News Today
Apr 26, 2024 12:00 pm EDT
in Health
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  • Viral respiratory infections are common and generally result in a few days of illness from which most people recover without treatment.
  • However, they can lead to severe disease, so most existing treatments aim to prevent existing infections from progressing.
  • A new study suggests a way of stopping viral respiratory infections before they have a chance to become severe.
  • The study found that a common antibiotic boosts the immune response to both SARS-CoV-2 and influenza in rodents, preventing severe disease and death.
  • The researchers propose that the antibiotic, neomycin, could be a cheap, effective way to prevent and treat viral respiratory infections in people.

The COVID-19 pandemic focused attention on viral respiratory infections and how they can be prevented and treated.

With effective vaccines against SARS-CoV-2 — the virus that causes COVID-19 — severe disease is less common than it was at the start of the pandemic, but there are still few effective treatments for this and other viral respiratory infections.

Currently, doctors use antivirals to try and prevent progression of these infections, with monoclonal antibodies and convalescent plasma for combating severe disease.

Now, a study led by researchers from Yale has found that a cheap, widely available antibiotic might reduce the risk of severe disease from viral respiratory infections.

The study found that neomycin, applied inside the nose, caused a strong immune response in mice and hamsters which protected against infection with both SARS-CoV-2 and influenza A.

And a small group of healthy people treated with a common nasal ointment containing neomycin — Neosporin — showed a similar immune response.

The study is published in PNAS.

William Schaffner, MD, professor of preventive medicine in the Department of Health Policy, and professor of medicine in the Division of Infectious Diseases at Vanderbilt University Medical Center, Nashville, TN, not involved in the study, commented on the findings for Medical…

Read the full article here

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Medical News Today

Medical News Today

Medical News Today is a web-based outlet for medical information and news, targeted at both the general public and physicians. All posted content is available online, and the earliest available article dates from May 2003. The website was founded in 2003 by Alastair Hazell and Christian Nordqvist.

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