- Researchers assessed the association between vitamin D supplementation and the incidence of dementia.
- They found that vitamin D supplementation was linked to a lower dementia incidence.
- Further studies are needed to certify the results.
Over 55 million people live with dementia worldwide, which is expected to rise to
Interventions that can affect dementia risk factors are being explored to slow disease progression. One such risk factor is vitamin D deficiency.
Some studies have found that vitamin D may aid the clearance of amyloid beta aggregates—one of the hallmarks of Alzheimer’s disease (AD). However, studies have produced conflicting results on whether vitamin D improves cognitive function.
Other
Further studying the link between vitamin D supplementation and cognitive decline could help develop preventative strategies for dementia.
Recently, researchers assessed the link between vitamin D supplementation and incident dementia. They found that vitamin D supplementation is linked to lower incidence of dementia.
The study was published in
For the study, the researchers analyzed data from 12,388 people from the National Alzheimer’s Coordinating Center, who were dementia-free at the start of the study. Their average age was 71 years old.
Altogether, 37% of the cohort took at least one of three vitamin D supplements: calcium-vitamin D, cholecalciferol, and ergocalciferol.
In their analyses, the researchers also accounted for demographic, clinical, and genetic variables, such as depression and APOE ε4 status—a gene variant linked to a higher risk of dementia.
After five years, the researchers found that 83.6% of those exposed to vitamin D supplements were alive and dementia-free. The same was true for 68.4% of…
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