- Endometriosis affects around 10% of females of reproductive age worldwide.
- In people with endometriosis, tissue similar to the endometrium, or uterine lining, grows outside the uterus, causing severe period pain and heavy bleeding, and, in some, infertility.
- This tissue can form lesions, scar tissue, and organ adhesions.
- Although currently available treatments can help to alleviate symptoms, there is currently no cure for endometriosis.
- New research has shown that a monthly antibody injection that reduces lesions, scar tissue, and organ adhesions in monkeys with endometriosis.
According to the
Symptoms, including severe pain during menstruation, heavy menstrual bleeding, back and pelvic pain, pain during intercourse, and, in some people, problems with fertility, occur when tissue similar to the endometrium, or uterine lining, grows outside the uterus.
Currently, endometriosis
Although these treatments can alleviate the symptoms, the condition is currently regarded as incurable.
Now, a Japanese study has found that a monthly injection of an engineered antibody that targets interleukin-8 (IL-8), an
The research, published in Science Translational Medicine, suggests that this might lead to the first disease-modifying therapy for people with endometriosis.
The researchers used
Female macaques menstruate, just like human ones, with an
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