- Chronic alcohol use can cause painful nerve damage known as alcoholic neuropathy, and people with alcohol use disorder experience allodynia — hypersensitivity to pain — during alcohol withdrawal.
- A newly developed mouse model of withdrawal-related allodynia and alcohol-induced neuropathic pain showed that both pain conditions activate microglia (immune cells) in the spinal cord tissue, but the inflammatory pathways involved are different.
- These findings could potentially lead to the future development of targeted therapies for withdrawal-related allodynia and alcohol-induced neuropathic pain.
According to the National Survey on Drug Use and Health,
People with alcohol use disorder are unable to stop or control their alcohol consumption, even when it causes problems to their health, relationships, and work.
Additionally, people with alcohol use disorder experience allodynia during
Understanding how alcohol misuse causes pain is complicated by the fact that pain is not only a symptom of alcohol misuse but also a frequent cause of increased alcohol use.
The potential of alcohol to
Research suggests that alcohol has a
To date, the biological mechanisms…
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