- Researchers say artificial intelligence has helped them identify two subtypes of prostate cancer.
- They say the new prostate cancer “evotypes” could be used to better diagnose patients and improve treatments.
- They add that the findings could be especially valuable in treating a disease where both under-treatment and over-treatment can occur.
Researchers are reporting that a program aided by artificial intelligence (AI) has helped them identify two distinct subtypes of prostate cancer — a finding they say could improve diagnosis and treatment of the disease, including preventing unnecessary surgery.
Their
In it, researchers from the University of Oxford and the University of Manchester in England identified the prostate “evotypes” using AI to analysis DNA data.
Researchers studied changes in prostate cancer samples from 159 people using genomic sequencing to identify the pair of evotypes.
The researchers say the findings could help develop a genetic test that, when combined with conventional staging and grading, could provide patients with a precise prognosis and treatment.
Rupal Mistry, PhD, a senior science engagement manager at Cancer Research UK, which helped fund the study, told Medical News Today that the research “laid the foundations for personalized treatments for people with prostate cancer, allowing more people to beat their disease.”
“Our research demonstrates that prostate tumors evolve along multiple pathways, leading to two distinct disease types,” said Dr. Dan Woodcock, a lead study researcher and a group leader in translational data science at the Nuffield Department of Surgical Sciences at the University of Oxford, in a press statement. “This understanding is pivotal as it allows us to classify tumors based on how the cancer evolves rather than solely on individual gene mutations or expression patterns.”
Dr. Michael Morris, the prostate cancer section head at the Memorial…
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