A rare genetic mutation never seen before protected a man with an inherited form of Alzheimer’s from developing the disease for decades.
He is the second person found to have such protection, following a report in 2019 of a woman with a different mutation (SN: 1/26/20). Both mutations may have staved off the disease for years by acting in similar ways in the brain, an insight that could lead to new treatments for all forms of Alzheimer’s, scientists report May 15 in Nature Medicine.
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