Once on the path to eliminating syphilis, the United States has reversed course, with cases of the infectious disease surging.
From a low of under 32,000 cases in 2000, the number of people with syphilis has rocketed to more than 207,000 in 2022, the U.S. Centers for Disease Control and Prevention reported in January. That’s 62 cases per 100,000 people.
The crisis is hitting pregnant people and babies especially hard. The maternal rate for syphilis during pregnancy rose from 87 per 100,000 births in 2016 to 280 per 100,000 births in 2022, the CDC reported on February 13. Without treatment, pregnant people can pass a syphilis infection to the fetus. That can cause congenital syphilis and lead to miscarriage, stillbirth, premature birth, severe health problems after birth or the infant’s death. More than 3,700 babies were born with syphilis in 2022, roughly ten times the number in 2012.
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